What this is
This atlas maps the structural fault lines of the male fruit fly central nervous system: how sensory signals can reach motor neurons, where the wiring is thinnest, and what breaks when parts are removed. It is built from the MaleCNS v1.0 connectome (Berg et al., Cell 2026) and the exact outputs of our analysis pipeline. Every number on this site is generated from the same results files as the paper, so the two can never disagree.
Two synapse thresholds are shown throughout. An edge between two neurons is kept only if it carries at least that many synapses: 5, the common weak-connection cutoff, and 11, the noise threshold used in the MaleCNS paper itself.
Key numbers
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How to read this atlas
Min-cut atlas
The exact minimum sets of edges whose removal disconnects all sensory-to-motor routes. These are mathematical facts about the graph, computed exactly, not statistical claims. Start here for the hard structural findings.
Lesion explorer
What happens when nodes or edges are removed at random versus removed by targeting rules (high out-degree, approximate betweenness, cut membership, edge weight). These comparisons are exploratory. None of the targeted-versus-random tests survived correction for multiple comparisons, so treat every pattern on that page as a lead for future work, not a finding.
Provenance
Data: MaleCNS v1.0, released 2026-06-08 under CC BY, via neuprint.janelia.org (dataset male-cns:v1.0).
Paper: Berg et al., "Sexual dimorphism in the complete Drosophila male central nervous system connectome", Cell 189(18), 2026. DOI: 10.1016/j.cell.2026.08.015
Analysis code and full results: github.com/akramahmed1/malecns-fault-lines